Predictors of Voiding Dysfunction following Uphold Mesh Repair for the Treatment of Pelvic Organ Prolapse
IUGA Academy. ZIXI L. Jun 30, 2018; 212901
Topic: Pelvic Organ Prolapse

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Predictors of voiding dysfunction following uphold Mesh repair for the treatment of pelvic organ prolapse

Zixi, L1; Yi-Yin, L1; Kun-Ling, L1; Cheng-Yu, L1


Introduction: Current treatment of pelvic organ prolapse (POP) with Uphold mesh repair offers high cure rates but some patients encountered voiding dysfunction after the surgery.

Purpose: The aim of our study was to identify the factors associated with voiding dysfunction after Uphold mesh repair for the treatment of pelvic organ prolapse.

Methods: One hundred and ten women with symptomatic POP stage II to IV were scheduled for Uphold mesh surgery. All subjects underwent urinalyses, UDI-6, IIQ-7, ICI-Q, POPDI-6, and pelvic examination using the POP quantification (POP-Q) staging system before and after surgery.

Results: Twelve (10.9 %) of 110 women reported voiding dysfunction after Uphold mesh surgery. We performed a univariate analysis of patients’ characteristics to identify the predictors of surgical failure after TVM. There was no difference between two groups as to body mass index, and urodynamic parameters (P>0.05). However, we found that age over 71, advanced and bothersome cystocele, preoperative concomitant urinary hesitancy and incomplete emptying, (P < 0.05) were significant predictors of voiding dysfunction following Uphold mesh surgery. Multivariate logistic regression showed the similar results.

Conclusions: Advanced and bothersome cystocele, age over 71, and preoperative concomitant urinary hesitancy and incomplete emptying were 3 significant predictors of voiding dysfunction after Uphold mesh repair. Women need to be counselling about above predictors before surgery.


Work supported by industry: no.

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