Prevalence and Risk Factors of Pelvic Organ Prolapse Among Women at Risk For Metabolic Syndrome in Southern Philippines Medical Center
IUGA Academy. Baliton-Veliganio A. Jun 30, 2018; 212935
Topic: Pelvic Organ Prolapse
Dr. Andrea Kristina Baliton-Veliganio
Dr. Andrea Kristina Baliton-Veliganio

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Prevalence and risk factors of pelvic organ prolapse among women at risk For metabolic syndrome in southern Philippines medical center

Baliton-Veliganio, AK1; Que, G1; Derecho, CM1

1: Southern Philippines Medical Center

Introduction: Certain metabolic factors increase risk for pelvic organ prolapse (POP). The components of metabolic syndrome (MS) as a modifiable risk factor in association with POP severity if identified, will potentially help prevent progression of POP and its need for surgery.

Objective: The purpose of this study was to identify modifiable metabolic risk factors of POP and its relation to POP severity among Filipino women.

Method: A prospective cross-sectional design was used in this study. A total of 194 women either diagnosed at risk for metabolic syndrome or with metabolic syndrome were included in the study. The NCEP/ATP III (National Cholesterol Education Program (NCEP) / Adult Treatment Panel III was used to describe the criteria for MS and the Pelvic Organ Prolapse Quantification (POP-Q) system was used to measure the POP severity. Patients were also probed for questions on possible risk factors related to POP. The following were assessed : Classification of physical activity by level of intensity using the Exercise and Physical Activity Guide for Health Promotion (2006) by the Tokyo Ministry of Health; Stress Urinary Incontinence (SUI) symptoms using the Stamey Urinary Incontinence Score; and Overactive bladder symptoms using questions taken from the Pelvic Floor Distress Inventory (PFDI) questionnaire.

Results: Only 14.3% of women at risk or are currently diagnosed with MS have POP (stage 1-4). In patients with MS, only BMI and NSD were positively correlated with pelvic organ prolapse at p-values of 0.0023 and 0.0091, respectively. The odds of having POP with MS is significant in the following components: the elevated fasting glucose (OR 1.052), BP above 130/85 mmHg (OR 1.018), and a >80cm waist circumference (OR 1.041)

Conclusion: BMI and the number of NSDs appear to be correlated with pelvic organ prolapse. Results however showed that MS in general did not influence POP severity. Individual components of MS such as waist circumference, elevated fasting glucose and blood pressure are more likely to develop POP or will have increased severity with an odds ratio of more than 1.


Work supported by industry: no.

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